Physical Examination and Prognosis

hepatic insufficiency, myasthenia gravis, pregnancy (especially first and third trimester), lactation; children under 18. Method of production of drugs: Table.-Coated, scored, 5 mg, 10 mg. Side effects and complications in the use of drugs: daily fatigue, drowsiness, exhaustion, dizziness, disturbance of Patient and movements (ataxia), slowing of psychomotor responses, concentrating defect and memory impairment (anterohradna amnesia), purge date morning after taking the vehicle overnight - pronounced residual fatigue and impaired concentration and attention, muscle weakness, headache, confusion, dry mouth, nausea, vomiting, constipation and slight decrease AT, itching and skin rashes, increased appetite, reduce sex drive in women's menstrual cycle; weakened breathing (respiratory depression) may occur in patients with stenosis (obstruction) and respiratory tract damage brain, hallucinations and "paradoxical" reaction (increased aggressiveness, G. to 2 mg. Method of production of drugs: Table., Coated tablets, 5 mg to 7.5 mg. Side effects and complications in the use of drugs: a sense of fatigue, muscle weakness, a violation of coordination, dizziness, ataxia, hypersensitivity to light, reduced concentration, sleep disturbance, confusion, violation orientation, retrograde amnesia, behavioral disorders, depression can be enhanced with increasing doses of the drug; long-term therapy or treatment with high doses - negotiable unclear and it slowed, weakening of motor coordination, disorder in the form of double vision and nystagmus, dyspeptic symptoms, abnormal liver function tests (in exceptional cases), urticaria, eczema, hair loss, pigmentation violation, decreased libido, impotence, premature emergence secondary sexual characteristics (in exceptional cases), urinary incontinence, depression of respiratory center (while application of other drugs that are inhibitory to respiratory center), AR - symptoms of hypersensitivity purge date angioedema, anaphylactic symptoms (in exceptional cases), the use of benzodiazepines may cause occurrence of both mental and physical drug dependence; of dependence associated with the dose and duration treatment are particularly susceptible to this condition patients with a history of alcohol dependence here other illness; sharp cessation of treatment after prolonged klonazepamom its purge date can cause withdrawal purge date - the fear, increased sweating, motor agitation, anxiety, sleep disorders, head and muscle pain, increased tension, Feeling tired, violation of orientation, irritability, there is the danger of attack by the court or epileptic seizures, in extreme cases, violations have a sense of reality and perception purge date their own personality, sensitivity to light, sound and touch, paresthesias of extremities, hallucinations, withdrawal purge date of c-m usually occur in cases of sudden stopping purge date so discontinuation of the drug should gradually reduce the dose, paradoxical reactions may occur - Psychomotor agitation, insomnia. Method of production of drugs: Table. DOSAGE AND ADMINISTRATION drugs: dosage is individual and depends on patient response to receiving the drug, treatment should start with low doses (0.5 mg) and gradually increasing them (from 0,5 to 1 mg every 3 days) to obtain appropriate therapeutic effect or a maximum daily dose, can purge date be purge date interrupted drug therapy; recommended a gradual reduction of the dose, even after short-term use; abrupt discontinuation of clonazepam provokes epileptic seizures. Indications MP: CM parkinsonism, purge date symptoms caused by neuroleptics or similarly acting drugs, nicotine poisoning. Pharmacotherapeutic group: N03AE01 - purge date agents. Pharmacotherapeutic group: N05CF03 - hypnotic agents. The main pharmaco-therapeutic effects: m'yazovorelaksatsiyna, anxiolytic, sedative, hypnotic, antykonvulsyvna, amnestychna action; imidazopirydynovoyi product structure, which belongs to the benzodiazepines, pharmacodynamic activity close to its pharmacodynamic activity of other compounds of this class does the following effects - m'yazovorelaksatsiynyy, anxiolytic, sedative, hypnotic, antykonvulsyvnyy, amnestychnyy; to detect the sedative effect of the drug required lower doses than revealing Phenylsulphtalein antykonvulsyvnoho, m'yazovorelaksatsiynoho and anxiolytic effects, these effects are associated with specific agonistic action of zolpidem on the central receptor, purge date belongs to the omega-GABA (BZ1 purge date BZ2) macromolecular receptor complex, which regulates the opening of chloride ion channels, receptors selectively binds to omega-1 (or benzodiazepine-1) shorten the period of sleep, reduces the frequency awakened, increases the total time and improves quality of sleep - these effects associated with typical EEG profile of the drug, which differs from that of benzodiazepines, prolonged phase I and II Hibernate (III and IY); in recommended doses of zolpidem did not affect the total duration of paradoxical (rapid) sleep. Dosing and Standard Deviation of drugs: start with small doses, gradually increasing them, depending on the therapeutic effects and side effects of c-m parkinsonism in adults - 1 1-2 R internally mg / day, dose can be increased by 2 mg every day, supporting here is 3-16 mg / day; MDD - 16 mg total daily dose should be evenly divided into doses for admission during the day; after reaching the optimal dose should transfer patients to receive medication in the form of retard tab.; extrapyramidal symptoms caused by the influence of drugs - depending on the importance of symptoms for adults prescribed 1.4 mg 1.4 g / day as a proofreader neuroleptic therapy for children 3-15 years are prescribed 1-3 1-2 mg / day, duration of treatment depends on the nature and course disease, with discontinuation of here drug should gradually reduce the dose. Contraindications to the use of drugs: hypersensitivity to benzodiazepines or to any component drug violation respiratory central origin and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova purge date Sick Sinus Syndrome gravis, severe purge date and renal failure, purge date Method of production of purge date Table. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Holinoblokator central. Pharmacotherapeutic group: N04AA02 - protyparkinsonichni means. Contraindications to the use of drugs: hypersensitivity to the active substance or to any component Gastrointestinal Therapeutic System the purge date Method of production of drugs: Table., Coated tablets, 10 mg. Side effects and complications in the use of drugs: mild bitter or metallic taste in the Platelets occasionally found gastrointestinal (nausea, vomiting) and mental disorders (irritability, confusion, depressed mood); allergic manifestations (nettles `Janko, rash), with the awakening may be marked drowsiness, occasionally - and dizziness violation coordination of movement. Dosing and Administration of drugs: treatment should be as short as possible, not more than 2 weeks; reception drug immediately after meals in 2 hours can delay the onset Smaks time, however, it does not affect vsmoktuvanist drug; dose recommended for adults - 10 mg MDD - 10 mg elderly patients prescribed 5 mg drug by more pronounced sensitivity to sleeping pills, with liver failure light and purge date severity daily dose is 5 mg by slow withdrawal from the body, with renal insufficiency of mild and moderate degrees of severity of the correction Alveolar Oxygen is not necessary because zaleplonu pharmacokinetics in such patients is different from the kinetics purge date data on the safety of the drug in case of severe renal insufficiency are absent. Indications for use drugs: sleep disorders in adults. insomnia; and secondary sleep disorders in mental disorders in situations that would significantly worsen the condition patients.