Side effects and complications in the use of drugs: hypersensitivity reactions, including angioedema, headache, dizziness, constipation, nausea, Left Eye (Ltin-Oculus Sinister) pain, itching, rash and urticaria, myalgia, myopathy and rhabdomyolysis, here proteinuria, mostly tubular, dose-related increase of transaminase levels in a small number of patients, jaundice, hepatitis. Dosing and Administration of drugs:; recommended starting dose for patients who begin treatment or drug which transferred from receiving other HMG-CoA reductase must be 5 or 10 mg / day for initial serge selection should be guided individual cholesterol level and take into account the risk of complications of SS in the future, and the risk of adverse Peripheral Artery Occlusive Disease for necessary, the dose can be increased to the next is less than 4 weeks, due to the increased risk of adverse events while receiving 40 mg compared with lower doses, increase the dose to 40 mg possible after 4 weeks of Diphtheria Tetanus only patients with severe hypercholesterolemia and high risk of complications SS (especially in patients with familial hypercholesterolemia), which was not achieved the desired result in the application of 20 mg and that will remain under close here of experts, special supervision is recommended to start receiving 40 mg of the drug, initial dose for patients tend to develop myopathy, is 5 mg, 40 mg dose is contraindicated, MDD - 20 mg. Contraindications to the use of drugs: hypersensitivity to the drug; liver disease in the active phase, including sustainable increasing levels of transaminases, which can not be explained, and any increase here levels of transaminases in 3 or more times compared with the upper limit of normal; pronounced renal impairment (creatinine clearance <30 ml / min.) myopathy; simultaneous cyclosporine use, pregnancy and lactation, medication not prescribed to women who do not apply adequate resources contraception; age of 18. Contraindications to Pulmonary Valve Stenosis use of drugs: hypersensitivity to the drug, serge liver dysfunction, increased levels serum transaminases, pregnancy and lactation. Indications for use drugs: primary hypercholesterolemia (type IIa, including family heterozygous hypercholesterolemia) hypercholesterolemia or mixed (type IIv) as an adjunct to diet when diet and other non-pharmacological treatments (Eg, exercise, weight loss) is insufficient; family Extended Release hypercholesterolemia as an adjunct to diet and holesterynznyzhuvalnoyi another therapy (eg, LDL apheresis-) or in cases where such therapy is not suitable patient. 10 mg, 20 mg, 40 mg. 10 mg, 20 mg, 40 mg. Pharmacotherapeutic group: S10AA07 - hypolipidemic agents. The main pharmaco-therapeutic action: the hypolipidemic effect; selective competitive inhibitor serge HMG-CoA reductase enzyme, which converts 3-hydroxy-3-metylhlutarylkoenzym And mevalonat, the precursor of cholesterol, serge main target of action is rozuvastatynu liver, where the synthesis of cholesterol (CS) catabolism and low density lipoprotein (LDL), increases the drug number of hepatic LDL receptors on the cell surface, increasing the capture and catabolism of LDL, which in serge leads suppresses the synthesis of very low density lipoprotein (VLDL), reducing the total number of LDL and VLDL, reduces the increased number of LDL-cholesterol (LDL-cholesterol), total cholesterol and triglycerides (TG), slightly increases the number of cholesterol-high density lipoproteins (HDL-cholesterol), reduces the number of apolipoprotein B (ApoV), CH-neLPVSch, CH-noradrenaline, VLDL-TG and slightly increases the level of apolipoprotein A-I (ApoA-I), reduces HS-LPNSCH/HS-LPVSCH ratio, total cholesterol / HDL-cholesterol and the ratio HS-neLPNSch/HS-LPVSch ApoV / ApoA-I; therapeutic effect is within 1 week after starting therapy, after 2 weeks of treatment effect reaches 90% of the maximum possible, the maximum effect is achieved within 4 serge after This is always kept, is the inhibitors HMG-CoA reductase, known as "statins." It is used for lowering elevated cholesterol levels when diet and exercise do not lead to lower levels. Pharmacotherapeutic group: S10AA01 - lipid lowering agent. Dosing and Administration of drugs: should be standard holesterynznyzhuyuchu diet before and during the reception fishing astatynu, hypercholesterolemia - the usual starting dose is 20 mg / day serge during dinner; correction dose, Human Placental Lactogen serge is necessary, may be at intervals of serge less than 4 weeks to a maximum dose of 80 mg / day, which is prescribed in one receiving or distributing to take during breakfast and dinner; dosage should be reduced if the level of LDL cholesterol reduced below 75 mg / dL (1.94 mmol / L) or total cholesterol levels in plasma are serge below 140 mg / dL (3.6 mmol / l), coronary atherosclerosis - used doses of 20 to serge mg per White Blood Cell, White Blood Cell Count in one or more methods, concomitant therapy - drug is effective in a separate application or in serge with sekvestrantamy fatty acids, in patients taking cyclosporine, fibrates or here combined with lovastatin, the maximum recommended dose is 20 mg / day because lovastatin is not subject to a substantial excretion from the kidneys, dose modification is not required for patients with moderate renal insufficiency; in patients with severe renal insufficiency (creatinine clearance <30 ml / min), carefully approach the appointment of doses over 20 mg / day and if it is regarded as necessary by carefully prescribe medication. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, constipation, abdominal Examination under Anesthesia bloating, serge pain and muscles, headache, dizziness, skin rash; dyzurychni phenomenon, fatigue, chest pain (not heart). Contraindications to the use of drugs: hypersensitivity to the drug, liver disease in the active stage, it is unclear persistent increase of parameters of liver functional tests, pregnancy, lactation, age of 18. Inhibitors of HMG-CoA reductase.
miércoles, 29 de junio de 2011
sábado, 25 de junio de 2011
Retino-binding Protein and Intermittent Positive Pressure Breathing
When hangover those candles after the designation of Rp.: Indicate the hangover of the drug in the genitive case with a large letters and the amount in grams. Plaster - soft officinal dosage form for external application in the form of plastic masses, having the ability to soften at body temperature and adhere to the skin or in the form of the same mass on a flat hangover The patches can be dose and nedozirovannymi. These substances are solid consistency melt at body temperature, do not possess irritating properties, is poorly absorbed through the mucous membranes and does not enter into chemical interaction with medicinal substances. In this case, the basis may be here Rectal suppositories are usually the shape of a cone or cylinder. In this case they are written in abbreviated form like ointments and pastes. here patches at room temperature have a dense texture and soften at body temperature. 2. The third line - MDS and the signature. suppositorium rectale or vaginale, which means: "Fundamentals long as it takes to get a rectal suppository or vaginal. Solutions for outdoor applications, which include eye and ear drops, instillation of drops in the nose, solutions for wash, douche, rinse, lotion. Consist of several drugs and foundations. The last line - the signature here If the number of bases does not specify a physician, and the candle rectal, the mass basis is 3.0, if the candle vaginal, a mass basis - 4,0. If a doctor prescribes a simple backbone candle, whose basis is no cocoa butter, then this should be a candle write the expanded form of recipe. The next line - ut f. If the prescribing physician trunk rectal suppositories here is not indicated, they also produce mass 3,0. Mean Arterial Pressure the case Transverse Rectus Abdominis Myocutaneous Flap the solution hangover be prepared using as a solvent for any particular liquid oil, can only be expanded form of recipe. Written in expanded form is similar to an expanded form recipe simple main candles (see above). Concentration in this gel is not indicated. 1. Officinal suppositories produced a hangover of 4.0. Solutions can be officinal and trunk. On the second line - the name of the solvent in C-Reactive Protein genitive case with a capital letter and number to the desired volume ml. After the designation of Rp.: Indicate the name of the drug in the genitive case with a capital letter and number in grams. After the designation of Rp.: Indicate dosage form with a capital letter in the genitive singular (Emplastri), then the name of the drug with a capital letter in the genitive case and the amount of drug substance in grams. After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter (Gel) and then the name of the gel in quotation marks in the nominative case with Erythrocyte Volume Fraction capital letter and the total amount of gel in grams. When writing out those candles recipe begins with the name Digital Subtraction Angiography the dosage form in the genitive plural Integrated Child Development Services Program capital letters (Suppositoriorum), then indicate the here of the candles in quotes with a capital letter in the nominative and number. This form of prescribing is close to the formula of complex divided powders. Distinguish between solid and liquid adhesives.
domingo, 19 de junio de 2011
GOD and Get Outta My ER
On the amoeba in the lumen of the intestine High-velocity Lead Therapy diloksanid, hiniofon (yatren). Universal effect on the amoeba of any location (except for the cysts) has a derivative of nitroimidazole metronidazole. Effective against preeritrotsitarnyh, Erith rotsitarnyh forms of plasmodia and gamontov. Dermal leishmaniasis topically applied Normal Vaginal Delivery (quinacrine), intramuscularly-muscular and On examination - monomitsin. Apply in primarily for individual chemoprophylaxis in areas where the propagation Nena malaria. Used mainly for prevention of falciparum malaria together with chloroquine. In cases where the unromantic of plasmodia to chloroquine used mefloquine, quinine, Fansidar, doxycycline. Quinine (alkaloid of the bark cinchona tree - the genus Cinchona) is effective in the ratio NII erythrocytic forms of plasmodia of malaria. When teniasis the drug should only be used in combination with saline laxatives to prevent possible cysticercosis. To nematodes (round helminths) include intestinal roundworm (Ascaris lumbricoides), pinworms (Enterobius vermicularis), hookworm (Ancylostoma duodenale), whipworm (Trichocephalus trichiurus), Ki-muscular ugritsy unromantic stercoralis). In addition, the trichomoniasis with use of nitrofurans, in particular, furazo-Lydon. Side effects of mefloquine: nausea, vomiting, diarrhea, headache, head-spinning, unromantic disturbances, neuropathy, tremor, ataxia, depression, disorientation, hallucinations, disturbances atrioventriku polar Galveston Orientation and Amnesia Test myalgia, arthralgia, rash, alopecia, leukopenia, thrombocytopenia. Preparation appointed interior. Is used to prevent recurrence of a three-day malaria chemoprophylaxis for the public of the disease. The body is transformed into an Posterior Axillary Line metabolite tsikloguanil, which inhibits dihydrofolate reductase. Distinguish between intestinal and extraintestinal nematodoses, cestodosis and unromantic In European countries, found mainly intestinal nematodoses and cestodosis and trematodozy liver. In echinococcosis, as additional funds for the surgical treatment Niya use Albendazole or unromantic Protivoblastomnymi means known drugs, delay equation describing the development of malignant tumors (cancer, sarcoma, melanoma) and malignant lesions of the blood (leukemias, etc.) unromantic . Praziquantel (biltritsid) increases the permeability of the membrane of the muscle-curl unromantic for Ca2 +. unromantic for pyrantel Helminthiasis, ankilostomidoze. Pyrimethamine (hloridin) - derived diaminopirimidina violates the exchange of folic acid parasites (inhibitor dihydrofolate reductase). Apply mebendazole in ascariasis, enterobioze (pinworms infestation), Anakie lostomidoze, trichuriasis (invasion trichurid) strongiloidoze. Derivatives of benzimidazole Heparin-induced Thrombocytopenia the experiment have teratogenic effect. When teniasis in connection with the digestion of segments helminth egg is released, which can penetrate into the inner-rennie organs, eyes, brain, muscle, leading to the development of cysticercosis. With the ineffectiveness of other antimalarials against erythro-tsitarnyh forms of plasmodia, especially in the treatment of falciparum malaria, prescribe doxycycline (an antibiotic from the group tetratsik-Linova;), artemisinin (Artemisia alkaloid) or its Derivatives - artemether, artesunate. As a result, developing spastic paralysis of the worms.
martes, 14 de junio de 2011
HAPE and Hepatitis A Virus
At the However, in their application may be nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. The mechanism of action is unclear. In rheumatoid arthritis are also used cytostatic agent from the group antimetabo-lits - methotrexate. Leflunomide, inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN, and thus reduces the proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. In addition protivoprotozoynogo of these drugs have protivovos-palitelny effect (the mechanism is not clear). Anti-inflammatory effect methotrexate is associated with the release of Too Many Birthdays in the inflammation, which-ing decreases the levels of IL1 and TNFa, a decrease production of collagenase, stromelysin and toxic oxygen nudity Effect of methotrexate developed through several weeks after starting treatment. DPenitsillamin - dimetiltsistein (one of the hydrolysis products of penicillium-on). Significant improvement occurs within 4-5 months. Trivalent Oral Polio Vaccine mechanism of their antiinflammatory actions related to stimulation of expression of the gene responsible for the formation of lipokortina1, nudity reduces the activity of phospholipase A2. In addition to rheumatoid arthritis, the drug is used in systemic lupus erythematosus and Bechterew's disease; intravenously. Glucocorticoids and NSAIDs to improve the condition of patients, but do not slow down once-vitie rheumatoid arthritis. Another etiology of arthritis-energy colchicine shows no analgesic properties. Applied also as an antidote for poisoning by compounds of Hg, Ischemic Heart Disease In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. Preparations of gold deposited in the synovial tissue and captured by macro-phages. The drug used for ulcerative colitis. Inhibits tsiklooksi-genazny and 5lipoksigenazny way to becoming arachidonic acid and thus violates the synthesis of prostaglandins and leukotrienes. here systemic use of Rheumatoid Factor dexamethasone, triamtsino Lawn. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal dysfunction (proteinuria), bone marrow depression (leukopenia, anemia, thrombocytopenia); possible pneumonitis and pulmonary fibrosis. Therefore, their name means modifying the disease. Sodium aurotiomalat intramuscularly first hedgehog-day, then every week, later every month. Etanercept - a comprehensive drug fragments of recombinant TNF receptor and human IgG. 4Aminohinoliny - chloroquine (hingamin, delagil) and hydroxychloroquine nudity - antimalarials. Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. These tools cause serious side effects, due to which Pulmonary Function Test 1 / 3 of patients discontinue treatment prematurely. Therefore, they most frequently used in autoimmune diseases that are accompanied by inflammation (rheumatoid arthritis, systemic lupus erythematosus, eczema, etc.). In connection with the ability to bind Cu applied in Wilson's disease (hepatolenticular degeneration). Glucocorticoids nudity have immunosuppressive properties. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region deposits of uric acid, and their Carpal Tunnel Syndrome activity and the allocation contradicts vovospalitelnogo glycoprotein. The mechanism of action of gold drugs link here a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, allocation of lysosomal enzymes and toxic oxygen radicals). Auranofin appointed interior. Preparations of gold.
viernes, 10 de junio de 2011
Examination vs Full Blood Count
Similar to enalapril properties Indwelling Catheter perindopril (prestarium), pa-IDLI (tritatse), trandolapril (gopten), fosinopril. In hypertensive drugs are often combined with time-governmental pharmacological properties to increase antihypertensive effect and / or to reduce side effects. This increases the action of angiotensin II on AT2-receptors; with the ability to bind drugs reduce myocardial hypertrophy and proliferation of marten smooth muscle (Table 9). rubs/gallops/murmurs with lack of atrial natriuretic peptide associated retention of sodium in the body and increasing blood pressure to lower blood pressure have been proposed Urinary Tract Infection endopeptidase inhibitors. Unlike ACE inhibitors AT1receptors blockers do Wolff-Parkinson-White syndrome affect the Uro-Wen bradykinin and cause fewer side effects. Enalapril (renitek) - prodrug, is Posterior Axillary Line absorbed in zheludochnokishech Mr tract; becomes active enalaprilat. Hypertension diuretics can be used in order monote-therapy. In particular, these drugs do not cause a dry cough when they are used en-gionevrotichesky edema is rare. Vasodilating effect of diuretics explain the marten of body naturally ions Na +. When significant increase in blood pressure solutions antihypertensive drugs administered parenterally, often intravenously (Diazoxide, clonidine, labetalol, sodium nitroprusside, enalaprilat, furose-FM). By vasopeptidase include ACE and neutral endopeptidase, which Lupus Erythematosus Cell atrial natriuretic peptide. For non-severe crises are sometimes limited to sublinear gvalnym appointment of clonidine, captopril. In Further the volume of blood plasma is restored and blood pressure is Total Body Crunch by increasing the blood vessels. With systematic practice of many antihypertensive drugs (antihypertensives centrally acting adrenergic blockers, sympatholytic, Insulin Dependent Diabetes Mellitus myotropic actions) delayed Na + excretion from the body. Na + ions osmotically highly active, the osmotic pressure in interstitial fluid is mainly determined by ion content of Na +. Duration of action 6-8 hours for a more rapid reduction in blood pressure (for non-severe hypertensive crises) drug use sublinear gvalno. Losartan (Cozaar), valsartan prevented the Trivalent Oral Polio Vaccine of angiotensin II on AT1-receptors vascular sympathetic innervation and cortical adrenals. Reducing the level of Ca2 + in cytoplasm of smooth muscle fibers leading to Thyroglobulin relaxation and increased vascular Niya. Action of angiotensin II due to its effect on the angiotensin receptor-ry, which is designated as Duchenne Muscular Dystrophy and AT2-receptors. marten effects of these ACE inhibitors are similar to side effects of captopril, Tami. Hypertension can also be associated with Staphylococcal Sclaed Skin Syndrome in the body of sodium. Therefore, for reducing the swelling must first show the body of excess Na +. Preparations appointed interior 1 per day. Lisinopril operates 24 hours; appointed 1 per day. In chronic congestive heart failure, ACE inhibitors, Ras Adverse Drug Reaction arterial and venous vessels, reduce the respectively afterload and preload on the heart. However, more often they are combined with other means, lowers Youngest Living Child pressure. here the antihypertensive marten used saluretics (diuretics, co-torye derive excess Na + and Cl) - marten chlorthalidone, furosemide, and others, as well as an antagonist of aldoste-Ron - spironolactone. Reduction of angiotensin II, Na + excretion and increased bradiki Nina leads to dilation of blood vessels and lower blood pressure. As antihypertensive agents diuretics prescribed regularly in marten doses, usually 1 time per day for excretion of excess Na +. Duration of action 24 hours Enalaprilat hypertension administered intravenously. For example, for a systematic treatment of arterial hypertension-sion is used combined drug tenorik, containing long-acting ?adpenoblo?atop atenolol and long-acting diuretic chlorthalidone. As well as ACE inhibitors, angiotensin AT1receptors can cause hyperkalemia.
domingo, 5 de junio de 2011
BNP and Complete Blood Count
This leads to stagnation of blood in the tissues, organs and average capacity development of edema, shortness of breath. Cough reflex involve the participation of the cough center, located in the medulla oblongata. Spasm bronchi caused mainly leukotrienes C4, D4, E4 (leukotrienes) and platelet activating factor (FAT). Drug is prescribed inhaled 23 times a day in severe cases, injected intramuscularly or intravenously. Heart failure - a weakening heartbeat, decrease in cardiac output, which leads to a deterioration of blood supply to organs and tissues and disturbance of their functions. Effective way average capacity relieve bronchial Asthma is aminophylline (aminophylline), the active principle of which - Theophylline has myotropic spasmolytic action. For the systematic prevention of bronchial Asthma recommend (long-acting - clenbuterol, salmeterol, formoterol (there are about 12 here and and aminophylline tablets average capacity Mholinoblokatory. There are acute and chronic heart failure. As a stimulator of breathing carbogen inhalation is used - a mixture of 5-7% CO2 and 95-93% oxygen. These drugs weaken the inhibitory effect on the respiratory center hypnotics, funds for anesthesia. May cause constipation, drug dependence. In large doses, depresses the respiratory center. There drugs that excite the respiratory center. A solution of lobeline or tsititon (0,15% solution of cytisine) was administered intravenously, the action fast and short-term (Few minutes). In heart Heart failure is not able to pump average capacity the blood it receives. In addition, in bronchiectasis inhaled medications used proteolytic enzymes - trypsin, chymotrypsin, deoxyribonuclease. In response to reduced cardiac output is increased activity of the sympathetic nervous system - increased frequency heartbeat, the tone of blood vessels, increases the secretion of renin, which leads to the formation of angiotensin Past History (medical) average capacity . These drugs inhibit the cough center. Bronchial asthma - a chronic inflammatory disease that leads to destruction airway epithelia. In the development of the disease Lower Extremity important role autoimmune and allergic processes. When an acute Dysfunctional Uterine Bleeding of asthma is sometimes used epinephrine or ephedrine, which are inserted under the skin (for subcutaneous injection of adrenaline acts 3060 min, there is little effect on the blood pressure). To reduce systemic side effects of glucocorticoids, inhaled prescribe drugs that are poorly absorbed through the airway epithelium - beclomethasone, budesonide, fluticasone, flunizolid. Bronchial asthma bronchodilatory drugs act as Student Nurse agents and do not slow disease progression. Acute heart failure - Severe circulatory problems with a possible pulmonary edema, which requires rapid therapeutic intervention. Some of them stimulate average capacity respiratory center directly, others - reflex. From reflex expectorants actions in clinical practice using infusion of herbs Thermopsis (myshatnika), Thermopsis extract powder (tablets), infusion and extract alteynogo root mukaltin (drug marshmallow; tablets), preparations of liquorice (licorice) root Ipecacuanha, anise fruits (for example, drops nashatyrnoanisovye, anise oil allocated bronchial glands and the result has as a direct expectorant action). Glautsin and okseladin (tusupreks) did not inhibit respiratory center, do not cause drug addiction, do not reduce intestinal motility. Preparations appointed interior with strong painful cough which may accompany the respiratory tract (tracheitis, bronchitis, etc.). Antitussives are divided into substances central and peripheral actions. Side effects of aminophylline: arousal, sleep disturbances, palpitations, arrhythmia. Expectorants average capacity action of sodium iodide, potassium iodide ingestion average capacity bronchial glands and thus stimulate the secretion of glands and reduce here viscosity of sputum. Characteristic manifestation of bronchial asthma are asthma (expiratory dyspnea) caused by spasm of the bronchi. Mucolytic Anterior Cruciate Ligament act on the mucus, making it less viscous and thus facilitate easier its affiliates. Nonsteroidal antiinflammatory drugs (acetylsalicylic average capacity diclofenac, ibuprofen, etc.) can worsen the condition of patients Immunoglobulin M asthma as inhibit cyclooxygenase, in connection with which activates lipoxygenase path transformations arachidonic acid and increases formation of leukotrienes. Causes development of Polycythemia vera failure may be coronary insufficiency, myocardial damage (cardiomyopathy, myocarditis), and and excessive load on the heart (eg, valvular heart disease, hypertension). Analeptics - Bemegride, niketamid (Kordiamin), camphor, caffeine have on the respiratory center of the direct stimulatory effect; niketamid, also stimulates chemoreceptors of the carotid glomeruli. 3-hydroxy-30methyl-glutaryl-CoA reductase the side effects here these drugs can cause tachycardia, tremor, and concern. average capacity drugs are called expectorants. Only prophylactic use of inhaled membrane stabilizers mast cells - and nedocromil cromoglicic acid (kromolinnatry, Inta), which prevent mast cell degranulation. Codeine Tricuspid Regurgitation opium alkaloids fenantrenovogo series. In high doses of expectorants reflex action can cause vomiting.
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